During a battle with Animo, a head strong Ben in hero mode, doesn't listen to reason from Max and Gwen, and gets engulfed in a weird energy light. Little does Ben know that the "self destruct" function on the Omnitrix has just been initiated, sending out a signal that reaches Tetrax (the Diamondhead alien). Tetrax comes to Earth and tells Ben they must travel through space to find the watch's creator, Azmuth. He's the only entity who can stop the Omnitrix from self destructing, saving not only Ben, but the galaxies as well! As Ben and Tetrax travel through space, Ben must only must fight off Vilgax and his robotic drones who've picked up the Omnitrix's signal, but also deal with Gwen who's stowed aboard, believing Ben can’t do anything without her. After landing on a dangerous prison planet where they believe Azmuth is being held, our heroes stage his daring rescue, only to discover it’s not Azmuth they've freed, but his wacky assistant, Myaxx. Myaxx then directs them towards...