ROC curves are used to evaluate the accuracy of markers for disease detection or prognosis. They provide a graphical means of comparing one or many continuous markers to a binary measure of disease, allowing determination of an optimal marker cutoff for positivity. Dr. Amalia Magaret from the University of Washington presents recent adaptations to the standard ROC curves, allowing for consideration of cost, inclusion of additional predictors of disease, and comparison and combination of predictive markers. Dr. Margaret Pepe in the department of biostatistics at the University of Washington developed many of these advances. (Series: Laboratory Medicine Grand Rounds)
Recent psychological research has revealed widely-held unconscious thought patterns that most people would rather not possess. In this program from the University of Washington psychology...
Low back pain is a common but unfortunately not very specific presentation for arthritis sufferers. There are, however, a number of pathologic conditions, which may require further attention. Dr....
Until recently, the identification of chromosome abnormalities that are responsible for congenital disorders and cancer has relied on the use of banded chromosome preparations and fluorescence in...
Recent changes in testing technologies for syphilis and HIV present diagnostic laboratories new opportunities and challenges. Matthew Golden, division of allergy and infectious disease at the...
Dr. Mark Wener from the University of Washington discusses recent trends in autoantibody testing, which includes testing for such conditions as lupus, rheumatoid arthritis, and other autoimmune...
Genomic heterogeneity is emerging as an important factor in determining tamoxifen benefit in breast cancer. Dr. Hannah Linden, Associate Professor of Medicine at the University of Washington, and a...
Will changing our national health-care system provide health care for more people? Can any health-care system make a population healthy? What is the biggest deterrent to good health in our nation?...
Learn more about herpes simplex virus (HSV) and research efforts to develop a vaccine. Dr. Lawrence Corey from the University of Washington presents recent data on HSV reactivation and shedding,...
Recent advances in the electronics industry have enabled access to a number of sophisticated technologies at low costs. Learn a few aspects of the use of these technologies in detecting...
Will changing our national health-care system provide health care for more people? Can any health-care system make a population healthy? What is the biggest deterrent to good health in our nation?...
